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The sideeffects reported by 10% of subjects in at least 1 clinical study Listed by prevalence: ( The Food and Drug Administration (FDA) has issued a notification alerting physicians who prescribe topiramate, and their patients, to the FDA: in more than 5% of an administered dose. Topiramate enhances GABAactivated chloride channels. In addition, topiramate inhibits excitatory neurotransmission, through actions on kainic acid and AMPA receptors. There is evidence that topiramate has a specific effect on GluR5 kainate receptors. It is used to treat Post Traumatic Stress DisorderBerlant JL, Van Kammen DP. Open label topiramate as primary or adjunctive therapy in chronic civilian posttraumatic stress disorder: a preliminary report. J Clin Psychiatry. 2002;63:981984.Wilding J, Van Gaal L, side effects on zoloft Rissanen A, what not to eat with coumadin Vercruysse F, Fitchet M; OBES002 Study Group. 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